TRPC1 and TRPM7 were reported to be expressed in H4-IIE rat liver hepatoma cell lines (Brereton et al., 2001; Barritt et al., 2008), while TRPM2 channels were recently linked to APAP-induced oxidative stress and Ca2+ overload in mouse hepatocytes (Kheradpezhouh et al., 2014). This evidence concerns the gene TRPM7 and hepatocellular carcinoma.