A work published by Zhang and colleagues described a down-regulation of miR-9 in iPSC-derived neurons (iPSC: induced pluripotent stem cells) of FTD/ALS patients with TDP-43 mutations; they explained their results as an a effect of decreased TDP-43 expression revealed in these neurons (Zhang et al., 2013). This evidence concerns the gene TARDBP and amyotrophic lateral sclerosis.