MAPK8 and cancer: It has been reported that JNK signal pathway is related to many physiological and pathological processes, such as neuron sprouting (Eminel et al., 2008), tubulin dynamics in migrating neurons (Kawauchi et al., 2003), and progression of cancer (Moon et al., 2008) and numerous other diseases (Salh, 2007; Mehan et al., 2011; Davies and Tournier, 2012).