MGLL and cannabis dependence: It is worth noting that in human genetic studies genetic variation in the gene coding for the CB1 receptor (CNR1), as well as for FAAH and MAGL (MGLL) has been reported to be associated not only with cannabis dependence, but also with substance use disorder in general and impulsive personality traits (Agrawal and Lynskey, 2009; Proudnikov et al., 2010; Wang et al., 2011; Bidwell et al., 2013; Clarke et al., 2013; Demers et al., 2014).