IL2 and infection: Th1 cytokines such as interleukin-2 (IL-2), interferon-γ (IFN-γ), and Tumour Necrosis Factor alpha (TNF-α) are the primary source for proinflammatory Th1 responses [11], in which they are effective in controlling infection with intracellular pathogens and for perpetuating autoimmune responses [12].