In addition, no significant differences could be detected for the fold change of CD86+ and HLA-DR+ cDC, neither for the secreted amount of IL-1β, IL-6, IL-12p70, IFN-α, and caspase-1 upon LPS and IFN-γ stimulation between the trained and sedentary MS patients after 12 weeks (Tables 3 and 4). Here, IL6 is linked to myeloid sarcoma.