TP53 and metastatic malignant neoplasm in the lymph nodes: We found that LDHA levels were positively correlated with ki67 status and distant metastasis (P = 0.013 and 0.001, respectively) but not correlated with age, menopause, tumor size, lymph node metastasis, clinical stage, local relapse, ER, PR, HER2, P53 or VEGF status among the 121 breast cancer patients (Table 1).