Analysis in a total sample of 5,911 individuals consisting of 4,834 normoglycemic subjects and 1,077 T2DM subjects improved the association of missense variant rs2231142 in ABCG2 from 7.82 × 10−8 (Table 1) in normoglycemic subjects to 1.31 × 10−10 in combined sample (Table 3). This evidence concerns the gene ABCG2 and type 2 diabetes mellitus.