AFP and neoplasm: Significant factors associated with higher cumulative risk of tumor recurrence by univariable analyses included AFP >100 ng/mL at the time of resection; tumor size >3cm; poor tumor differentiation; the presence of lymphovascular permeation; the presence of microsatellite lesions; HBV viral load >20,000 IU/mL pre-resection, at 1 and 6 months post resection; the presence of core promoter and C1653T mutations; patients with antiviral treatment before resection (Table 1) were identified.