During an ischemic stroke the eventual restriction of oxygen in the brain due to an obstruction leads to a cascade of events including hypoxia, increased expression of pro-inflammatory cytokines like tumor necrosis factor alpha (TNF-α) and interleukin-1beta (IL-1β), as well as increased release of the excitatory neurotransmitter glutamate [9]. This evidence concerns the gene IL1B and ischemic stroke.