Among individual complications, patients with hemangiomas < 10 cm had significantly less hemoglobinuria than did patients hemangiomas ≥10 cm (5.8% vs. 40.4%, P < 0.001); there was a trend also for less hemolytic hyperbilirubinemia (total bilirubin > 34.2 μmol/L) (P = 0.001), fever (≥ 38°C) (P < 0.001), elevated serum transaminase(including alanine transaminase and aspartate transaminase) (> 80 U/L) (P = 0.004) and anemia (hemoglobin <100 g/L) (P = 0.183) in the patients with hemangiomas <10 cm. The gene discussed is GPT; the disease is hemangioma.