APC and neoplasm: Moreover, while G:C‐T:A transversion mutations in Apc and Ctnnb1 (β‐catenin) genes extracted from the induced tumors and accumulation of β‐catenin in nuclei of the tumor cells have been found in Mutyh−/− mice treated with KBrO3, the same mutations in Apc have also been found in tumors of patients with MAP.