MSH2 and hereditary nonpolyposis colon cancer: Additionally, G:C‐A:T and A:T‐G:C transition mutations and G:C‐C:G and G:C‐T:A transversion mutations at glycogen synthase kinase 3β (GSK3β)‐mediated phosphorylation sites in Ctnnb1 were found in the induced‐tumors in Msh2‐deficient mice treated with KBrO3, consistent with the mutation sites and their spectra found in patient with HNPCC.