Tumours were then analysed for the presence of classical hallmarks of human glioblastoma multiforme (GBM) such as pleomorphic GFAP+ glial cells, mitoses, diffuse infiltrative growth, pseudopalisading microscopic necrosis and microvascular proliferation (Fig. 2b–d and Supplementary Fig. 5a,b). Here, GFAP is linked to neoplasm.