These cells have a high expression of mature endothelial cell antigens vWF, CD31, CD146, and KDR, and lack expression of the haematopoietic antigen, CD45.27 This study demonstrated impaired proliferation, adhesion, and migration of vessel wall EC derived from the superficial forearm veins in these patients compared to matched control subjects.27 Consistent with these observations, we found that SENCR expression was significantly reduced in vessel wall EC isolated from patients with premature CAD compared to control subjects (Figure 8d). Here, KDR is linked to coronary artery disorder.