For instance, the Arabidopsis dcl1-9 mutant (defective in miRNA biogenesis) and ago mutants (defective in miRNA activity) are impaired in PTI and display enhanced susceptibility to bacterial infection, whereas the Arabidopsis dcl1-7 mutant is more susceptible to infection by the fungal pathogen Botrytis cinerea (Weiberg et al. 2014) Also in Arabidopsis, the rdr6 mutant is more susceptible to bacterial and fungal infection (Katiyar-Agarwal and Jin 2010; Ellendorff et al. 2009). This evidence concerns the gene CD302 and bacterial infectious disease.