USP15 and cancer: We identified that the expression change of MIR381 (p-value < 0.83) contributes to the expression changes of RNA-binding protein 5 (RBM5) (p-value < 0.008) and ubiquitin specific peptidase 15 (USP15) (p-value < 6☓10-4) via significant miRNA regulations (p-value < 10-16) in cancer cells.