We identified that the change in the miRNA expression profile of MIR302a (p-value < 0.734) leads to the change in the gene expression profile of teashirt zinc finger homeobox 3 (TSHZ3) (p-value < 0.189), also known as zinc finger protein 537 (ZNF537), between normal liver cells and liver cancer cells (Fig. 4). The gene discussed is ZFHX3; the disease is liver cancer.