Most GJB2 and GJB6 mutations are associated with autosomal recessive non-syndromic hearing loss, but several dominant mutations, causing sensorineural HL or syndromic hearing loss (KID (MIM 148210), Vohwinkel (MIM 124500) syndromes, palmoplantar keratoderma (MIM 148350)) have been described [13]. The gene discussed is GJB6; the disease is Hodgkins lymphoma.