OLR1 and metastatic neoplasm: Moreover LOX-1 expression resulted strongly increased in the 72% of carcinomas (G1-G2;any T;N0), and strongly overexpressed in 90% of highly aggressive and metastatic tumours, as compared to normal mucosa (G2-G3;any T;N1,N2,M0,M1 vs NM: P< 0.001) (Figure 1f and Table 1b).