EPHA3 and cancer: Remarkably, in HMGA1P6 and HMGA1P7 overexpressing cells and MEFs we detected the upregulation of several cancer-related genes such as High Mobility Group A2 (HMGA2), Enhancer of Zeste Homolog 2 (EZH2), Vascular Endothelial Growth Factor (VEGF), and Ephrin Type-A Receptor 3 (Epha3), with respect to the control cells [100].