ITGA6 and colorectal carcinoma: The latter is well illustrated by the high level of rescue observed in the identification of iFOBT negative lesions with ITGA6. As expected from this complementarity, combining the data from the iFOBT test with ITGA6 in an algorithm referred to as the IF score showed significant improvement in the overall sensitivity for both Ad and CRC as compared with ITGA6 alone.