The inhibition of glycolysis by COUP-TFII knockdown is observed in all of our tested prostate cancer cell lines, including LNCaP, PC3, CWR22Rv1, VCaP and LNCaP-abl (Figure 3B and 3C, Supplementary Figure S4A and S4B), implicating a broad impact of COUP-TFII on glycolysis of prostate cancer cells. Here, NR2F2 is linked to prostate cancer.