This set of genes included forkhead box C1 (FOXC1), keratin 14 (KRT14), cyclin E1 (CCNE1), melanoma inhibitory activity (MIA) and secreted frizzled-related protein 1 (SFRP1), while expression of CDCA1 and MELK, (neither of which were detectable in MCF7), did not change following SOX11 depletion. The gene discussed is MELK; the disease is melanoma.