However, when AAA was categorized by severity, we found that HO activity following type 2 and 3 AAA expansions were significantly higher in the rosuvastatin group (31.0±9.7 versus 58.1±19.1 and 65.9 versus 86.6 pmol CO/h/mg FW, respectively, p<0.05). The gene discussed is HMOX1; the disease is triple-A syndrome.