For the case of Luminal A, Luminal B, HER2 and TN subtypes, we have found seven exclusive subtype-related pathways, including glycine serine and threonine metabolism pathway for Luminal B, glycerolipid metabolism, fatty acid metabolism, complement and coagulation cascades and bladder cancer for HER2 and small cell lung cancer and metabolism of xenobiotics by cytochrome p450 for TN. This evidence concerns the gene ERBB2 and urinary bladder cancer.