In contrast, quantitative real-time PCR and 3’-RACE-RFLP analysis revealed unreduced nonstop mRNA levels in the patient with mitochondrial neurogastrointestinal encephalomyopathy harboring a nonstop mRNA mutation (c.1416delC) in the TYMP gene [14]. This evidence concerns the gene TYMP and mitochondrial neurogastrointestinal encephalomyopathy.