CSF3 and heart failure: In our study population, the long-term (10 years) follow-up data, recently collected, confirmed the safety of the protocol and, remarkably, patients treated with G-CSF showed a significant improvement of the quality of life assessed by New York Heart Association (NYHA) functional class, Seattle Heart Failure Model, Minnesota Living with Heart Failure Questionnaire (p < 0.005) (unpublished data).