BCL2 and lung cancer: Given that transcriptional repression of Bcl2 was provoked secondary to the resveratrol-induced decrease in miR-21expression in in vitro models of pancreatic cancer [46] whereas miR-21 has been reported to be associated with poor drug treatment outcomes in lung cancer patients [26], it is tempting to investigate whether the miR-21/Bcl2 axis would represent a mechanism of action of resveratrol in the combat against drug resistance in NSCLC.