Bacterial asparaginase (L-Asparaginase amidohydrolase, E.C. 3.5.1.1) is a selective and highly effective chemotherapeutic agent extensively used in first-line treatment of acute lymphoblastic leukemia (ALL), acute myeloblastic leukemia (AML) and other tumor malignancies in human [1]. This evidence concerns the gene ASPG and acute lymphoblastic leukemia.