KCNB1 and Alzheimer disease: A previous in vivo study has shown that Aβ oligomers can modify Kv2.1 expression and promote increased channel synthesis.26 Moreover, increased expression has also been shown to enhance channel clusterization.27 To assess whether the increased Kv2.1 clusterization that we found in our AD model is dependent on higher levels of channel conglomeration but not synthesis, we performed a Kv2.1 western blot analysis in the two strains.