When the FC values and the genomic loci of the DEGs were specifically taken into consideration, negative regulators of inflammation (CD69, CLEC12A, CLEC12B, TNFAIP3), neutrophil granule proteins (LTF, OLFM4, AZU1, MMP8, DEFA4, CAMP), antigen processing and presentation proteins (CTSS, ERAP1), and regulators of immune response (LGALS2, BCL10, ITCH, CEACAM8, CD36, IL8, CCL4, EREG, NFKBIZ, CCR2, CD180, KLRC4, NFAT5) were found to be differentially expressed in BS patients with respect to controls (Tables 3, 5 and 6). The gene discussed is CEACAM8; the disease is Bloom syndrome.