In recent years the postprandial hyperglycemia has been recognized as an independent risk factor for the development of cardiovascular complications and oxidative stress in patients with DM [6], and structured exercise programs have shown to play an important role in glycemic control during the day, causing increased sensitivity to insulin for up to 48 h after the workout, which can assist in preventing hyperglycemic spikes [29]. Here, INS is linked to Hyperglycemia.