Our findings show that upregulation of miR-182 is associated with angiogenesis-induced myocardial hypertrophy and decreases the expression of branched chain aminotransferase 2 (Bcat2), forkhead box O3 (Foxo3), and adenylate cyclase type 6 (Adcy6). The gene discussed is FOXO3; the disease is cardiac hypertrophy.