By direct DNA sequencing in twenty-five individuals (15 PD patients and 10 normal controls), we identified 10 SNPs within the NFE2L2 gene, including 3 exonic SNPs, 2 intronic SNPs, 3 promoter SNPs, and 2 SNPs in 3′ region of NFE2L2 gene. The gene discussed is NFE2L2; the disease is Parkinson disease.