As shown in Fig. 3b, a significant down-regulation of Gal-3 protein was observed in EECs but not ESCs of eutopic endometrial samples from the endometriosis group compared to the control group (0.22 ± 0.05 vs 0.58 ± 0.07, p < 0.05). This evidence concerns the gene LGALS3 and endometriosis.