STAT3 and carcinoma of esophagus: For instance, hsa-let-7c has been shown to be associated with prognosis and to be a marker of sensitivity to cisplatin through the regulation of the IL-6/STAT3 pathway in patients with oesophageal cancer [14] and miR-141 has been found to exert anti-apoptotic effects that confers cisplatin resistance in oesophageal cancer cell lines, possibly through downregulation of YAP1 [15].