Mice lacking HO-1 are more susceptible to myocardial infarction [71] and atherosclerosis [72]; mice lacking NQO1 are more susceptible to chemically induced carcinogenesis [73] and chemical toxicity [74], and mice lacking G6PD exhibit increased renal oxidative stress [75] and are more susceptible to myocardial dysfunction [76]. Here, NQO1 is linked to atherosclerosis.