TP53 and Familial prostate cancer: These observations support the idea that differential signals to p53 variants on our array are real We found considerable overlap between potential antigen biomarkers of PCa identified by different analyses, notably BORIS BO which was unique to PCa in our 3-way Venn diagram analysis has been reported recently to correlate at mRNA level with prostate cancer aggression and is potentially able to activate the androgen receptor genes [43].