How to cite this article: Motamed MR, Nasiri F, Fereshtehnejad SM, Mehrpour M, Zamani B, Haghi-Ashtiani B, et al. Complicated orolingual angioedema after recombinant tissue plasminogen activator treatment in stroke patients under angiotensin converting enzyme inhibitor: Report of two cases. This evidence concerns the gene ACE and angioedema.