Duan et al. show that elevated serum levels of creatinine, malondialdehyde (MDA), and two acute kidney injury (AKI) markers cystatin C (Cys-C) and neutrophil gelatinase-associated lipocalin (NGAL) were significantly reduced under the baseline levels by HQH, while estimated glomerular filtration (eGFR) was improved [24]. Here, CST3 is linked to acute kidney injury.