We observed significantly enhanced IL-21R expression on CD19+ B cells in the whole group of pSS patients (mean ± SD: 3.434 ± 0.929 MFI versus 2.961 ± 0.585 MFI, resp., p = 0.0288) and in subgroup of patients with EGMs, compared to values measured in healthy individuals (mean ± SD: 3.578 ± 0.901 MFI versus 2.961 ± 0.585 MFI, resp., p = 0.0195) (Figure 2). The gene discussed is CD19; the disease is peeling skin syndrome.