We have also shown for the first time that seven of the known invasive breast cancer predisposition loci not previously shown to be associated with DCIS have comparable ORs for IDC and DCIS: rs4973768 (SLC4A7), rs3821902 (ATXN7) [26], rs10995190 (ZNF365), rs554219 (CCND1), rs3757318 and rs2046210 (ESR1). The gene discussed is ESR1; the disease is invasive breast carcinoma.