TRIM32 overexpression significantly repressed AB-mediated cardiac hypertrophy, as indicated by reduction in the ratios of heart weight to body weight (HW/BW), the ratios of HW to tibia length (HW/TL) (Figure 3D), the gross size of the heart (Figure 3E) and the cardiomyocyte cross-sectional area (Figure 3F) in TRIM32-TG mice compared with MCT mice. This evidence concerns the gene TRIM32 and cardiac hypertrophy.