IFNB1 and systemic lupus erythematosus: These findings were validated for RA patients and untreated patients with MS who were IFNhigh, as the microarray datasets used for validation of our findings in SLE and IFNβ-treated MS patients also contained gene expression data for RA patients (GSE17755, n = 112) and untreated patients with MS (GSE41846 and GSE41848, n = 62) (Fig. 4b) [33, 34].