OTUB1 and ovarian neoplasm: Altogether, the MAPPIT experiments identified OTUB1 (OTU de‐ubiquitinase, ubiquitin aldehyde binding 1), a member of the ovarian tumor domain protease (OTU) family of DUBs (Wang et al, 2009; Iglesias‐Gato et al, 2015), as a putative binding partner of RAS proteins (Fig 1A and B).