FASLG and lymphopenia: These methods include inducing T cell anergy and lymphopenia, decreasing synthesis of antibodies, increasing immunosuppressive cytokines (i.e., IL10 and TGF-β), upregulating inhibitory molecules of T cells (i.e., Fas ligand [FasL] and programmed death ligand-1 [PDL-1]), and recruiting regulatory T cells (Tregs) and myeloid derived suppressor cells (MDSCs) to subdue immune response [7–13].