To conclude, in our study we demonstrated a minor effect of the rs2071559 of KDR on markers of carotid atherosclerosis (CIMT, sum of plaque thickness) in subjects with T2DM, whereas we failed to demonstrate an effect of tested polymorphism of the VEGF gene (rs2010963) on markers of carotid atherosclerosis. Here, KDR is linked to type 2 diabetes mellitus.