The present study was thus designed to investigate the association between polymorphisms of the VEGF gene (rs2010963) and the KDR gene (rs2071559) and markers of carotid atherosclerosis (such as carotid intima-media thickness (CIMT), the number of affected segments of carotid arteries, and the sum of plaques thickness) in patients with T2DM. This evidence concerns the gene VEGFA and carotid atherosclerosis.