There were 236 cases (80.5%) with CADM1/TSLC1 positive expression in 293 cases of esophageal squamous cell carcinoma (ESCC), with 1 score in 20 cases, 2 scores in 41 cases, 3 scores in 41 cases, 4 scores in 93 cases, and 6 scores in 41 cases, respectively, and 57 cases were CADM1/TSLC1 negative expression (Figure 1(a)). This evidence concerns the gene CADM1 and esophageal squamous cell carcinoma.