In Kaplan-Meier survival analysis, we found that the overall survival (OS) of CADM1/TSLC1 negative group was significantly lower than that in CADM1/TSLC1 positive group, which was consistent with the results in other studies of esophageal squamous cell carcinoma (ESCC) [14], as well as skin squamous cell carcinoma [20], laryngeal carcinoma [13], meningioma [21], breast cancer [22], nasopharyngeal carcinoma (NPC) [23], lung adenocarcinoma [9], and colon cancer [12]. Here, CADM1 is linked to malignant colon neoplasm.