ERBB2 and gastric cancer: Although the FDA has approved everolimus for the treatment of advanced renal cell carcinomas that have not responded to treatment with other drugs (sorafenib and sunitinib) (March, 2009) [41] and hormone receptor positive and HER2-negative advanced postmenopausal breast cancer patients (July, 2012) [42] for the use of everolimus in the treatment of advanced gastric cancer; there is a need to select more suitable target populations.