Rearrangements of the ALK gene, which most often consists of a chromosome 2 inversion that leads to fusion with the echinoderm microtubule‐associated protein‐like 4 (EML4) gene, are found in approximately 2–7% of patients with NSCLC 1, 2, 3, 4. The gene discussed is ALK; the disease is non-small cell lung carcinoma.