Finally, SNP2 (rs11889341) is the most potent of several eQTL variants within the STAT4 risk locus is very strongly associated with SLE susceptibility (p<4.8 × 10-9), and impacts the transcription levels of STAT1 and STAT4 (Supplementary file 2). The gene discussed is STAT1; the disease is systemic lupus erythematosus.